This building was founded by the Noble Lady Marietta who obtained the Vatican’s approval to set up a monastery for the Discalced Carmelitan nuns. The monastery was built as an orphanage on St Margaret Hill in 1726 by the priests Fr Anton Barbara and Fr Pietru Saliba who were aided by a group of charitable ladies. There they lived as a community of the Third Order of the Discalced Carmelites and took care of the orphanage. Grandmaster Manoel de Vilhena insisted that the ladies should take the habit of the second Order and in 1739 seventeen nuns professed before Bishop Alpheron de Bussan.

The church which is annexed to the monastery was constructed in an old style with an elegant portico and a barrel-vaulted ribbed ceiling. It was consecrated in 1787.